Medical professionals use endoscopes to examine inside the body and even perform minor surgical procedures. And they do all this without the need for invasive surgery. One key performance requirement for endoscopes is a low friction, lubricious surface. For this, hydrophilic medical device coatings are applied on the surfaces to make them both safe and effective. These “slippery-when-wet” coatings reduce patient discomfort and improve navigation. They allow the endoscopes to move easily throughout the body. But they provide more than just a slippery surface. Hydrophilic coatings for endoscopes offer several benefits. For example, they can provide improved imaging by reducing fog and glare.
In this article we dive into the importance of hydrophilic coatings for endoscopy or gastroscopy. Get ready to learn the benefits of these coatings as well as the different types of hydrophilic coatings used.
Importance of Hydrophilic Coatings for Medical Devices

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The performance and safety of medical devices largely depends on the specialized coatings applied to their surfaces. These coatings modify the surface of the device, changing it’s properties and making it safer to use in the human body.
There are many coatings available in the market. And these coatings are used extensively. For example, recent market reports show the demand for medical device coatings is growing exponentially, with a rate (CAGR) of 9.8% between 2023 to 2032. The global market size is expected to reach USD 10.85 billion by 2032.
The right coating to use will be determined by the requirements of the specific medical device.
In general, the main goal of hydrophilic medical coatings (or any medical coating) is to enhance the following properties of the medical device:
- Durability
- Biocompatibility
- Corrosion Resistance
- Lubricity
- Adhesion (of the coating to the substrate)
- Sterilization
Medical coatings also help device manufacturers meet stringent regulatory standards. Their critical role in medical procedures is unmatched.
If you are new to these coatings make sure to check out our in-depth guide covering Hydrophilic Coatings for Medical Devices.
Intro to Hydrophilic Coatings and their Use in Medical Devices
The term “hydro” means water, while “philic” means affinity or love. Hydrophilic coatings are surface modifications that make surfaces “water-loving.”
The coated surface attracts surrounding water molecules, forming hydrogels with high lubricity and extremely low coefficient of friction. Their purpose is to make the surface “slippery-when-wet”.
Hydromer® advanced hydrophilic coatings help lower the risk of adverse reactions when medical devices come in contact with the human body. Their water loving properties make the medical device surface slippery. This allows for easy insertion and movement throughout the patient’s body while reducing discomfort and injury. It also significantly lowers the chances of complications caused by these devices. Specifically, it helps reduce fouling, thrombosis, and other medical complications that lead to longer hospital stays and increased healthcare costs.
Types of Hydrophilic Medical Coatings Used in Endoscopy
Hydrophilic coatings applied on medical scopes significantly improve their ease of use. These coatings help reduce friction and improve maneuverability.
Here is a list of hydrophilic coatings that can be used to improve the performance of such diagnostic medical devices.
1. Polymer-based Hydrophilic Coatings
These are the most popular types of hydrophilic coatings used. They are used in a variety of applications due to their level of flexibility.
Polymer-based coatings are made up of hydrophilic polymers. These include poly(acrylic acid), polyvinyl alcohol (PVA), and polyethylene glycol (PEG). Such materials have excellent water retention properties. This makes them a perfect fit for endoscopy.
These polymer-based hydrophilic coatings have two main purposes when used for endoscopes. Those are to improve navigation and ensure biocompatibility over extended periods. Hydromer®, Inc. is a leading manufacturer of polymer-based hydrophilic coatings. Hydromer Medical Device Coatings have the following properties:
- Highly lubricious
- Wettability
- Antimicrobial
- Drug-eluting capabilities
- Biocompatibility
- Low particulate
- Enhanced adhesion
- Thromboresistance to reduce blood clotting
- Anti-fog and condensation
2. Hydrogels
These coatings contain 90% water entrapped in a three-dimensional, hydrophilic polymer network. Hydrogels create a gel-like layer when they come in contact with surrounding liquids. This surface is extremely slippery-when-wet. And it has the ability to remain lubricated throughout the operational procedure.
Hydrogels are best suited for diagnostic applications requiring minimal friction in order to prevent tissue damage. A perfect example is the use of hydrogels with specific properties such as elasticity, degradation time, and swelling required in endoscopic submucosal dissection (ESD).
Learn more about Hydromer® Hydrogels.
3. Lubricious Coatings
Lubricious coatings are used in advanced endoscopic applications that require improved performance and safety. They may combine both hydrophilic and hydrophobic properties. Such coatings are made up of synthetic and naturally polymeric materials depending upon the functional requirements of the medical device. Such devices can be used multiple times.
Benefits of Hydrophilic Coatings for Endoscopes and Scopes

There are many benefits of applying hydrophilic coatings to diagnostic tools, such as endoscopes. They are particularly helpful in hard-to-reach areas. And they are especially beneficial during complex endoscopic procedures.
Let us discuss the top 5 benefits of hydrophilic coatings for endoscopy:
- Reduced Friction: Hydrophilic coatings make the scope’s surface “slippery-when-wet.” This creates a smooth layer with little to no friction. Such a lubricious layer helps with navigation and reduces discomfort. It also eliminates the risk of fouling and thrombosis. These are common complications when endoscopes are inserted into the human body.
- Improved Navigation: The water-attracting properties of hydrophilic coatings provide excellent lubricity when the endoscopes come in contact with bodily fluids. It allows endoscopic devices to move smoothly throughout the medical intervention. This helps reduce damage to tissues and also helps navigation through complex areas.
- Better Visibility: Hydrophilic coatings improve visibility during endoscopy. They do this by preventing two major problems associated with endoscopic lenses: fogging and glare. Debris can be easily removed to maintain clear vision throughout the procedure. These coatings also allow providers to clean the lenses post-endoscopy easier.
- Reduced risk of contamination: Advanced hydrophilic formulations are capable of breaking down dirt and impurities. This is commonly known as the photocatalytic property of hydrophilic coating. Hydromer antimicrobial hydrophilic coatings prevent the sticking of microbes on endoscopes and add another level of security against infections.
- Enhanced Safety & Comfort: Hydrophilic coatings make the endoscopic procedures less invasive. They also reduce post-endoscopic complications. The ease of insertion significantly reduces the risk of trauma and improves patient safety. The minimized drag and resistance prevent tissue irritation, abrasions, and potential injuries that lead to further complications, such as thrombosis.
Conclusion
Endoscopy is a complex medical procedure. It includes inserting flexible medical scopes deep within the human body for diagnostic and surgical purposes. Hydrophilic coatings for endoscopes have revolutionized such procedures. They make medical devices safer and more effective.
Such coatings, when applied on endoscopes, reduce patient discomfort during insertion. They help professionals obtain clear imaging by preventing fogging and tissue buildup. Hydromer, Inc. has 40+ years of experience manufacturing and supplying customized hydrophilic medical coatings.
Our company uses only the highest quality ingredients to manufacture best-in-class coating solutions. But we do not just offer off-the-shelf products. Rather, all of our hydrophilic coatings and hydrogels can be custom-formulated. This ensures you will get a solution that meets your specific product requirements.
Get In Touch with Hydromer
Our team includes highly qualified Ph.D. chemists, scientists, and regulatory experts. We can help you no matter what stage of the product development process you are in. What sets us apart from our competitors is the wide range of support services we offer our partners.
Here is a quick list of R&D and coating services offered by Hydromer:
- Research and Development (R&D) services
- Contract coating services
- Specialized Analytical Testing
- Custom Machine Building
- Turn-key Operations
- Technology Transfer Services
- Technical consulting and support services
Contact our team of experts today to learn more about our services.