Heparin Coating
Term: Heparin Coating
Category: Coatings
Definition: Heparin coatings are a type of biomedical surface treatment that immobilizes heparin. Heparin is a naturally occurring anticoagulant and it is coated onto the surfaces of medical devices to improve blood compatibility. When it is bound to the surface of devices, it reduces platelet adhesion, decreases protein deposition, and reduces the risk of thrombosis. This permits blood-contacting devices to function safely and effectively within the body.
How it Works: Heparin is a sulfated polysaccharide and interacts with antithrombin III to inhibit thrombin and factor Xa, thereby preventing the formation of fibrin clots.
Common Uses:
- Vascular catheters and stents
- Cardiopulmonary bypass and dialysis circuits
- Blood oxygenators and extracorporeal circulation systems
- Vascular grafts and heart valves
- Other implantable or blood-contacting medical device
Related Content and Resources:
Hydromer® Medical Device Coatings
Hydrophilic Coatings for Medical Devices: Intro, Benefits & Uses
