Hydromer is ISO 9001:2015 certified with TUV Rheinland of North America. ISO 13485:2016 is certified with BSI. 

FDA registered. Hydromer is ISO 9001:2015 certified with TUV Rheinland of North America. ISO 13485:2016 is certified with BSI.

Anti-thrombogenic Coatings

Hydromer®

Thromboresistant Coatings

Any medical device inserted into the body has the potential to cause blood clots which can lead to thrombosis or an embolism. Hydromer’s thromboresistant coatings are “slippery-when-wet” and are non-leaching. This can reduce blood clotting when coming in contact with medical devices, which can lead to atrial fibrillation, strokes, or even heart attacks. By reducing the adherence of blood to the surface of the device, thromboresistant coatings dramatically improve patient safety and clinical outcomes while also extending the lifetime of the product.

Suggested Applications:

  • Guidewires
  • Catheters
  • Stents
  • Implants
  • Lenses
  • Balloons
  • Pacemaker Leads
  • Shunts
  • And many more

Substrates:

  • Polyurethane
  • PVC
  • Chronoflex
  • Silicon

Resources:

Heparin Antithrombogenic Coatings

Independent Thrombus Reduction Study

RSC Thromboresistant Coatings Article

Hygea®

Heparin Antithrombogenic Coating

The Heparin coating is chemically bonded to the surface of medical devices, creating a reliable antithrombogenic catheter coating that inhibits thrombus formation effectively.

Thanks to the advanced heparin coating process, the heparin coated surface maintains its
integrity and functionality over prolonged use without degradation.

Suggested Applications:

  • Stent Grafts
  • Metal Implants
  • Introducer Sheaths
  • Central Venous Catheter (CVC)
  • Heart Valves
  • Vascular Grafts
  • Others

Product Advantages

Significant Anticoagulant Effect

Hygea® Heparin coating reduces protein and platelet adhesion through precise heparin coating techniques, delivering effective antithrombogenic catheter coating performance for medical devices.

Durable and Long-Lasting

The heparin coating process using UV or thermal curing ensures high bonding strength, maintaining coating integrity and function over long-term use in heparin coated catheters and other devices.

Nanometer-Level Precision

Ultra-thin, nanometer-level thickness and optimized graft density of heparinantithrombogenic coatings provide excellent anticoagulant effect while preserving device dimensions.

Reliable Biocompatibility

The coating offers excellent blood compatibility, making it a trusted antithrombogenic coating and heparinized coatings solution for vascular access and other medical applications.

Performance Tests

We have done a series of experiments with heparin coating, here are the results.
Uncoated PU

Completely covered with platelets and fibrinogen.

PU coated with cured heparin coating

Greatly reduces platelet adhesion.

Thrombosis reduced significantly

Thrombus weight before and after coating /g

Clotting time extended significantly

Clotting time before and after coating/min

jHemo PC®

Phosphorylcholine Hemocompatible Coating

The primary ingredient of the jHemo PC® Phosphorylcholine Hemocompatible Coating is phosphorylcholine (PC), the main lipid found on the outer layer of non-activated cell membranes. As an amphiphilic phospholipid (hydrophilic and lipophilic), it naturally resists protein and cell adhesion, forming an effective biomimetic coating for functional medical device coatings.

Suggested Applications:

  • Vascular Grafts
  • Neurological Guidewires and Catheters
  • Haemodialysis Catheters
  • Embolic Protection Devices
  • Vena Cava Filters
  • Peripherally Inserted Central Catheter (PICC)
  • Others

Product Advantages

Biomimetic Material Composition

As an amphiphilic phospholipid (hydrophilic and lipophilic), PC naturally resists protein and cell adhesion, providing a foundation for an effective hemocompatible coating.

Covalent Surface
Bonding

PC is covalently bonded to device surfaces, forming a stable phosphorylcholine surface coating that reduces thrombosis caused by protein aggregation.

Ultra-Thin,
Drug-Free Layer

Achieves nanometer-level coating thickness. Free of drugs, minimizing inflammatory responses and ensuring compatibility with sensitive vascular access and catheter applications.

Anti-Adhesion and Anti- Crystallization Properties

Water molecules surrounding PC create a biological "non-stick" surface.

Performance Tests

We have done a series of tests on jHemo PC® Phosphorylcholine Anticoagulant Coating, the following is the result of a comparative test.

SEM

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